教員紹介

教授

水元 一博

ミズモト カズヒロ
  • 看護学部
  • 看護学科
略歴 高木病院高邦会診療情報管理部長
前九州大学病院病院長補佐
前九州大学病院診療録管理室長
前九州大学病院がんセンター長
前九州大学病院医療連携センター長

【資格】
日本外科学会認定指導医・外科専門医
日本消化器外科学会認定医
日本がん治療認定医機構がん治療認定医
日本病院会認定診療情報管理士
最終学歴 九州大学 医学部 医学科 卒業
奈良県立医科大学 がんセンター腫瘍病理研究生 修了
九州大学 医学部 第一外科 専修生 修了
学位 博士(医学)
専門分野 診療情報管理(膵臓がん、消化器がん、診療情報管理)
主な教育研究業績

【著書】


・Mizumoto K,et al. ,Autophagy Is Required for Activation of Pancreatic Stellate Cells, Associated With Pancreatic Cancer Progression and Promotes Growth of Pancreatic Tumors in Mice,Gastroenterology,152(6):1492-1506,2017


・Mizumoto K,et al. ,Podoplanin expression in cancer-associated fibroblasts enhances tumor progression of invasive ductal carcinoma of the pancreas,Mol Cancer,12(1):168,2013


・Mizumoto K,et al.,REG4 is associated with carcinogenesis in the ‘intestinal’ pathway of intraductal papillary mucinous neoplasms,Mod Pathol,22(3):460-468,2009


・Mizumoto K,et al. ,Radiation enhances adenoviral gene therapy in pancreatic cancer via activation of cytomegalovirus promoter and increased adenovirus uptake.,Clin Cancer Res,14(6):1859-1867,2008


・Mizumoto K,et al. ,Quantitative Analysis of Human Telomerase Reverse Transcriptase in Pancreatic Cancer,Clin Cancer Res,12(7):2066-2069,2006


・Mizumoto K,et al. ,S100A11, a putative tumor suppressor gene, is overexpressed in pancreatic carcinogenesis,Clin Cancer Res,12(18):5417-5422,2006


・Mizumoto K,et al.,Quantitative assessment of telomerase activity and human telomerase reverse transcriptase messenger RNA levels in pancreatic juice samples for the diagnosis of pancreatic cancer.,Clin Cancer Res,11(6):2285-2292,2005


・Mizumoto K,et al.,The role of S100A6 in pancreatic cancer development and its clinical implication as a diagnostic marker and therapeutic target.,Clin Cancer Res,11(21):7785-7793,2005


・Mizumoto K,et al. ,Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions,Cancer Res,64(9):3215-3222,2004


・Mizumoto K,et al. ,Cell-based protein delivery system for the inhibition of the growth of pancreatic cancer: NK4 gene-transduced oral mucosal epithelial cell sheet,Clin Cancer Res,9(8):3158-3166,2003


・Mizumoto K,et al. ,Co-cultivation of pancreatic cancer cells with orthotopic tumor-derived fibroblasts: fibroblasts stimulate tumor cell invasion via HGF secretion whereas cancer cells exert a minor regulative effect on fibroblasts HGF production.,Cancer Lett,190(1):105-112,2003


・Mizumoto K,et al. ,Radiation stimulates HGF receptor/c-Met expression that leads to amplifying cellular response to HGF stimulation via upregulated receptor tyrosine phosphorylation and MAP kinase activity in pancreatic cancer cells.,Int J Cancer,104(5):542-549,2003


・Mizumoto K,et al. ,Radiation-induced increase in invasive potential of human pancreatic cancer cells and its blockade by a matrix metalloproteinase inhibitor, CGS27023,Clin Cancer Res,8(4):1223-1227,2002


・Mizumoto K,et al. ,Tumor suppression through angiogenesis inhibition by SUIT-2 pancreatic cancer cells genetically engineered to secrete NK4,Clin Cancer Res,8(10):3243-3249,2002


・Mizumoto K,et al.,Effect of serum depletion on centrosome overduplication and death of human pancreatic cancer cells after exposure to radiation.,Cancer Lett,170(1):81-89,2001


・Mizumoto K,et al. ,Possible role of telomerase activation in the multistep tumor progression of periampullary lesions in patients with familial adenomatous polyposis Am J Gastroenterol,96(4):1261-1265,2001


・Mizumoto K,et al.,Quantitative analysis of hTERT mRNA expression in colorectal cancer,Am J Gastroenterol,96(6):1895-1900,2001


・Mizumoto K,et al.,A possible role for centrosome overduplication in radiation-induced cell death,Oncogene,19(46):5281-5290,2000


・Mizumoto K,et al.,Centrosome abnormalities in human carcinomas of the gallbladder and intrahepatic and extrahepatic bile ducts.,Hepatology,31(1):59-64,2000


・Mizumoto K, Farber JL,Growth inhibition and cell killing by N-methyl-N-nitrosourea:Metabolic alterations that accompany poly(ADP-ribosyl)ation.,Arch Biochem Biophys,319(2):512-518,1995


・Mizumoto K,et al. ,Programmed cell death (apoptosis) of mouse fibroblasts is induced by the topoisomerase II inhibitor etoposide.,Mol Pharm,46(5):890-895,1994


・Mizumoto K,et al.,Inhibitory effect of butylated hydroxyanisole administration on pancreatic carcinogenesis in Syrian hamsters initiated with N-nitrosobis(2-oxopropyl)amine,Carcinogenesis,10(8):1491-1494,1989


・Mizumoto K,et al. ,Modulation of N-nitrosobis(2-hydroxypropyl)amine-induced carcinogenesis by clofibrate in hamsters.,Carcinogenesis,9(8):1421-1425,1988


・Mizumoto K,et al. ,Rapid production of pancreatic carcinoma by initiation with N-nitroso-bis(2-oxopropyl)amine and repeated augmentation pressure in hamsters. ,J Natl Cancer Inst,80(19):1564-1567,1988


【リサーチマップ】


https://researchmap.jp/read0043285


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